Evaluation of the Efficiency of Micro fragmented Adipose Tissue Injection Versus Bone Marrow Aspiration Concentrate Injection in Patient with Temporomandibular Joint Osteoarthritis

Authors

1 Demonstrator of Oral and Maxillofacial surgery, Oral and maxillofacial resident, At al zahraa university hospital.

2 Professor of Oral and Maxillofacial surgery, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt.

3 Professor of plastic and reconstructive surgery, Faculty of Medicine for Girls, Al-Azhar University

4 Associate professor of Oral and Maxillofacial surgery Cairo university, Cairo, Egypt.

5 Researcher in the Department of Oral and Dental Genetics, Institute of Human Genetics and Genome Research, National Research Center

Abstract

Purpose: This study was performed to evaluate the effect of micro fragmented adipose tissue injection and bone marrow aspiration concentrate injection in patient with temporomandibular joint osteoarthritis. Material and methods: Eighteen participants with TMJ osteoarthritis were divided into three groups, six participants in each group, group A: injected with hyaluronic acid (control group), group B: injected with micro-fragmented adipose tissue (MFAT), group C: injected with bone marrow aspiration concentrate (BMAC). All patients were assessed preoperatively and postoperatively at 1day,1week, 2week, 1month, 3 months, and 6 months for pain level, maximum interincisal opening, lateral, protrusive movements, joint tenderness and disk position with MRI after 6 months. Results: In the three groups, all clinical variables showed statistically significant discrepancy postoperatively. Conclusion: Despite the shortcomings of the current study the following could be concluded: MFAT and BMAC had a promising effect on treatment of TMJD.

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